UK-371804 HCl

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Selleck Chemicals

S8457-5MG

€144,00 EUR
€144,00 EUR
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UK-371804 HCl is an inhibitor of Serine Proteases used in studies of protease biology. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to proteolytic processing and cleavage-dependent signaling in inflammation models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By inhibiting Serine Proteases, UK-371804 HCl can be used to examine proteolytic processing and cleavage-dependent signaling. This target class is commonly examined through protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping. In inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Serine Proteases
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays
  • Phenotypic profiling in inflammation models

Overall, UK-371804 HCl is appropriate when a defined chemical perturbant is needed to connect Serine Proteases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Serine Proteases
Target Class:
Protease
Research Area:
Inflammation
CAS No.:
256476-36-5
Molecular Weight:
422.29
Formula:
C₁₄H₁₆ClN₅O₄S·HCl
SMILES:
CC(C)(C(=O)O)NS(=O)(=O)C1=CC2=C(C=C1)C(=CN=C2N=C(N)N)Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.