UBCS039

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Selleck Chemicals

SKU:S8909-5MG

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UBCS039 is an activator of Sirtuins used in studies of Autophagy and Epigenetic Regulation. In practice, this places the compound in experiments that measure autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation in aging, autophagy, and cancer models.

By activating Sirtuins, UBCS039 can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In aging, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Sirtuins
  • Pathway perturbation studies connected to Autophagy and Epigenetic Regulation
  • Gain-of-function pathway-activation studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, UBCS039 is appropriate when a defined chemical perturbant is needed to connect Sirtuins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Sirtuins
Target Class:
Epigenetic Regulator
Pathways:
Autophagy • Epigenetic Regulation
Research Area:
Aging • Autophagy • Cancer • Epigenetics
CAS No.:
358721-70-7
Molecular Weight:
247.29
Formula:
C₁₆H₁₃N₃
SMILES:
C1=CC=C2C(=C1)NC(C3=CC=CN32)C4=CN=CC=C4
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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