Trpm4 Antibody
BiCell Scientific
SKU:11024-50UL
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Protein Function
When you need to assess Trpm4 with attention to cellular organization, this antibody provides a focused option. Trpm4 is a membrane protein linked to solute movement and gradient maintenance. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Following Trpm4 across perturbations can help separate expression effects from compartment shifts.
Experimental Applications
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing.
Common experimental questions that benefit from target tracking include:
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
Workflow Perspective
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
For challenging targets, pairing Trpm4 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
For challenging targets, pairing Trpm4 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format variant when your project demands Trpm4 readouts that respect preparation constraints.
- Targets:
- TRPM4
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of mouse Trpm4 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q8TD43
- Homology:
- Synthetic peptide sequence is identical to rat sequence (shows 93.8% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C