Trpc6 (N-Terminus) Antibody

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BiCell Scientific

SKU:11016N-50UL

Regular price €305,00 EUR
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Blocking Peptide
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Protein Function

Build reproducible readouts by using this antibody to evaluate Trpc6 N-Terminus across matched sample sets. Trpc6 N-Terminus is a membrane-embedded regulator of ionic or osmotic balance in cells. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.

Following Trpc6 N-Terminus across perturbations can help separate expression effects from compartment shifts.

Experimental Applications

Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.

In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy. Kidney disease modeling efforts may include this target when exploring podocyte stress responses and structural change.

Common experimental questions that benefit from target tracking include:

  • relative abundance across engineered constructs
  • surface versus intracellular pool distribution
  • stimulus-dependent trafficking and turnover
  • patterns consistent with apical or basolateral sorting

Workflow Perspective

If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Document normalization choices so collaborators can reproduce the same interpretation.

If your study spans multiple model systems, it can help to define a shared reference condition for Trpc6 N-Terminus so cross-sample contrasts stay meaningful.

Pair this regular format format with stable controls to keep Trpc6 N-Terminus measurements coherent over time.

Targets:
TRPC6
Research Area:
Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (19-aa) derived from the N-terminal cytoplasmic region of human Trpc6 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q9Y210
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C