Trpc6 (C-Terminus) Antibody
BiCell Scientific
SKU:11016-50UL
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About the Target
Designed to help you examine Trpc6 C-Terminus, this antibody supports studies where protein context matters. Trpc6 C-Terminus is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Monitoring Trpc6 C-Terminus alongside context markers can improve interpretation when phenotypes are subtle.
Research Context
Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
- relative abundance across engineered constructs
Variant Considerations
When assay conditions are still being tuned, a regular-format antibody supports stepwise adjustment of buffers and incubation steps. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Trpc6 C-Terminus patterns can be compared across experiments without guesswork.
If your study spans multiple model systems, it can help to define a shared reference condition for Trpc6 C-Terminus so cross-sample contrasts stay meaningful.
Use the regular format variant when your project demands Trpc6 C-Terminus readouts that respect preparation constraints.
- Targets:
- TRPC6
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (18-aa) derived from the C-terminal cytoplasmic region of mouse Trpc6 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y210
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 72.2% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C