Trpc5 (C-Terminus) Antibody - FFPE Validated

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BiCell Scientific

SKU:11015-FFPE-50UL

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Size
Blocking Peptide
Quantity
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About the Target

When you need to analyze Trpc5 C-Terminus with attention to cellular organization, this antibody provides a focused option. Trpc5 C-Terminus is a channel or transporter associated with regulated flux across cellular membranes. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.

Monitoring Trpc5 C-Terminus alongside context markers can improve interpretation when phenotypes are subtle.

Research Context

Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions. Kidney disease modeling efforts may include this target when exploring podocyte stress responses and structural change.

Consider these angles when interpreting target-level changes:

  • relative abundance across engineered constructs
  • patterns consistent with apical or basolateral sorting
  • stimulus-dependent trafficking and turnover

Variant Considerations

For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

For challenging targets, pairing Trpc5 C-Terminus measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.

If your study spans multiple model systems, it can help to define a shared reference condition for Trpc5 C-Terminus so cross-sample contrasts stay meaningful.

Use the fixed-section variant when your project demands Trpc5 C-Terminus readouts that respect preparation constraints.

Targets:
TRPC5
Research Area:
Cell Signaling • Neuroscience
Application:
IHC-P
Reactivity:
Human • Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (16-aa) derived from the C-terminal cytoplasmic region of human Trpc5 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q9UL62
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C