Trpc2 Antibody - FFPE Validated
BiCell Scientific
SKU:11012-FFPE-50UL
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Protein Function
To connect mechanism with measurement, this antibody lets you explore Trpc2 in pathway-driven studies. Trpc2 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Tracking Trpc2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Experimental Applications
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
- surface versus intracellular pool distribution
Workflow Perspective
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
If your study spans multiple model systems, it can help to define a shared reference condition for Trpc2 so cross-sample contrasts stay meaningful.
When interpreting Trpc2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Choose the fixed-section format to study Trpc2 in a way that stays anchored to pathway logic.
- Targets:
- TRPC2
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal region of mouse Trpc2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9R244
- Homology:
- Synthetic peptide sequence is identical to rat sequence (no human Trpc2 gene)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C