Trk-A (NTRK1) Antibody
BiCell Scientific
SKU:06021-50UL
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Protein Function
This antibody supports experimental designs that examine Trk-A with interpretable controls and clear contrasts. Trk-A is a membrane or scaffold factor linked to neurotransmission and circuit development. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.
Following Trk-A across perturbations can help separate expression effects from compartment shifts.
Experimental Applications
Because many neuronal proteins form complexes, interpreting signal changes can benefit from complementary controls and timing. Time course design can be decisive when regulation is transient or compartment dependent.
In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Common experimental questions that benefit from target tracking include:
- comparison across differentiation time courses
- regional localization along neurites and synaptic compartments
- interaction tendencies with scaffold or receptor partners
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.
For challenging targets, pairing Trk-A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Use the regular format option to keep Trk-A analysis aligned with planned contrasts and endpoints.
- Targets:
- NTRK1
- Research Area:
- Cell Signaling • Developmental Biology • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (13-aa) derived from the C-terminal intracellular region of mouse Trk-A protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P04629
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 84.6% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C