Treprostinil

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Selleck Chemicals

SKU:E4846-5MG

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Treprostinil is an agonist of Prostaglandin Receptors used in studies of Immune Signaling and GPCR Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics in inflammation models.

By activating Prostaglandin Receptors, Treprostinil can be used to examine cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Prostaglandin Receptors
  • Pathway perturbation studies connected to Immune Signaling and GPCR Signaling
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Treprostinil is appropriate when a defined chemical perturbant is needed to connect Prostaglandin Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Prostaglandin Receptors
Target Class:
GPCR
Pathways:
Immune Signaling • GPCR Signaling
Research Area:
Inflammation
CAS No.:
81846-19-7
Molecular Weight:
390.51
Formula:
C₂₃H₃₄O₅
SMILES:
CCCCC[C@H](O)CC[C@@H]1[C@H]2Cc3cccc(OCC(=O)O)c3C[C@H]2C[C@H]1O
InChIKey:
PAJMKGZZBBTTOY-ZFORQUDYSA-N
PubChem:
6918140
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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