Toremifene
Selleck Chemicals
SKU:E4848
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Toremifene is a modulator of Estrogen/Progesterone Receptors used in studies of Hormone Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation in endocrinology, infectious disease, and neuroscience models.
By modulating Estrogen/Progesterone Receptors, Toremifene can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology, infectious disease, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Estrogen/Progesterone Receptors
- Pathway perturbation studies connected to Hormone Signaling
- Context-dependent response profiling and mechanism comparison
- Reporter-gene, receptor-binding, and transcriptional assays
Overall, Toremifene is appropriate when a defined chemical perturbant is needed to connect Estrogen/Progesterone Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology, infectious disease, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Estrogen/Progesterone Receptors
- Target Class:
- Nuclear Receptor
- Pathways:
- Hormone Signaling
- Research Area:
- Endocrinology • Infectious Disease • Neuroscience
- CAS No.:
- 89778-26-7
- Molecular Weight:
- 405.96
- SMILES:
- CN(C)CCOc1ccc(/C(=C(/CCCl)c2ccccc2)c2ccccc2)cc1
- InChIKey:
- XFCLJVABOIYOMF-QPLCGJKRSA-N
- PubChem:
- 3005573
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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