Toll-like receptor 7 (TLR7 or CD287) Antibody - Western Blot Validated
BiCell Scientific
SKU:64107-WB-50UL
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About the Target
To connect mechanism with measurement, this antibody lets you examine Toll-like receptor 7 in pathway-driven studies. Toll-like receptor 7 is a lineage-associated marker that supports stratification of immune populations in model systems. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol TLR7.
Research Context
Experimental perturbations such as cytokine exposure can reshape marker abundance and localization patterns. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- activation-dependent changes across stimulation conditions
- assessment of surface versus internalized pools
- comparisons across differentiation or polarization states
Variant Considerations
When samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
If your study spans multiple model systems, it can help to define a shared reference condition for Toll-like receptor 7 so cross-sample contrasts stay meaningful.
When interpreting Toll-like receptor 7, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
The denaturing-format option supports mechanistic reading of Toll-like receptor 7 when interactions and context are the focus.
- Targets:
- TLR7
- Research Area:
- Cell Signaling • Developmental Biology • Immunology • Inflammation
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse TLR7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9NYK1
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C