Tetraspanin-26 (TSPAN26 or CD37) Antibody - FFPE Validated
BiCell Scientific
SKU:10226-FFPE-50UL
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About the Target
This antibody supports efforts to examine Tetraspanin-26 and interpret it within interaction networks. Tetraspanin-26 is an extracellular or receptor-linked component that coordinates matrix engagement with cytoskeletal remodeling. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol CD37.
Research Context
Comparative experiments can separate expression differences from changes in adhesion structure abundance. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Consider these angles when interpreting target-level changes:
- remodeling after changes in substrate or mechanical stress
- focal adhesion versus diffuse membrane distribution
- effects of adhesion inhibitors or matrix composition
Variant Considerations
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing Tetraspanin-26 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Tetraspanin-26 patterns can be compared across experiments without guesswork.
Use the fixed-section version to relate Tetraspanin-26 behavior to upstream cues and downstream consequences.
- Targets:
- CD37
- Research Area:
- Developmental Biology • Immunology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) derived from the C-terminal cytoplasmic region of mouse Tetraspanin-26 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P11049
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 93.3% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C