Tetracycline
Selleck Chemicals
SKU:S4490-25MG
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Tetracycline is an inhibitor of CK2 used in studies of kinase signaling. In practice, this places the compound in experiments that measure phosphorylation signaling, target engagement, and selectivity relationships in cancer, cell signaling, and infectious disease models.
By inhibiting CK2, Tetracycline can be used to examine phosphorylation signaling, target engagement, and selectivity relationships. This target class is commonly examined through biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping. In cancer, cell signaling, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving CK2
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
- Phenotypic profiling in cancer, cell signaling, and infectious disease models
Overall, Tetracycline is appropriate when a defined chemical perturbant is needed to connect CK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- CK2
- Target Class:
- Kinase
- Research Area:
- Cancer • Cell Signaling • Infectious Disease
- CAS No.:
- 60-54-8
- Molecular Weight:
- 444.43
- Formula:
- C₂₂H₂₄N₂O₈
- SMILES:
- CN(C)C1C2CC3C(=C(O)C4=C(C=CC=C4O)C3(C)O)C(=O)C2(O)C(=C(C(N)=O)C1=O)O
- InChIKey:
- OFVLGDICTFRJMM-WESIUVDSSA-N
- PubChem:
- 54675776
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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