Tamoxifen Citrate
Selleck Chemicals
SKU:S1972-250MG
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Tamoxifen Citrate is a modulator of Estrogen/Progesterone Receptors and HSP90 and related targets used in studies of Apoptosis and Autophagy and related signaling programs. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation in apoptosis, autophagy, and cancer models.
By modulating Estrogen/Progesterone Receptors and HSP90 and related targets, Tamoxifen Citrate can be used to examine caspase-associated cell-death signaling and survival decisions and autophagic flux, lysosomal turnover, and stress adaptation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Estrogen/Progesterone Receptors and HSP90 and related targets
- Pathway perturbation studies connected to Apoptosis and Autophagy and related signaling programs
- Context-dependent response profiling and mechanism comparison
- Reporter-gene, receptor-binding, and transcriptional assays
Overall, Tamoxifen Citrate is appropriate when a defined chemical perturbant is needed to connect Estrogen/Progesterone Receptors and HSP90 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Estrogen/Progesterone Receptors • HSP90 • Estrogen Receptor • ATPases
- Target Class:
- Nuclear Receptor
- Pathways:
- Apoptosis • Autophagy • Hormone Signaling
- Research Area:
- Apoptosis • Autophagy • Cancer • Cell Signaling
- CAS No.:
- 54965-24-1
- Molecular Weight:
- 563.64
- Formula:
- C₂₆H₂₉NO·C₆H₈O₇
- SMILES:
- CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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