TAK-715
Selleck Chemicals
SKU:S2928-10MG
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TAK-715 is an inhibitor of p38 MAPK used in studies of MAPK / ERK Signaling and Immune Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-mediated signaling and inflammatory effector responses in cancer, cell signaling, and inflammation models.
By inhibiting p38 MAPK, TAK-715 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-mediated signaling and inflammatory effector responses. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving p38 MAPK
- Pathway perturbation studies connected to MAPK / ERK Signaling and Immune Signaling
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, TAK-715 is appropriate when a defined chemical perturbant is needed to connect p38 MAPK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- p38 MAPK
- Target Class:
- Kinase
- Pathways:
- MAPK / ERK Signaling • Immune Signaling
- Research Area:
- Cancer • Cell Signaling • Inflammation
- CAS No.:
- 303162-79-0
- Molecular Weight:
- 399.51
- Formula:
- C₂₄H₂₁N₃OS
- SMILES:
- CCC1=NC(=C(S1)C2=CC(=NC=C2)NC(=O)C3=CC=CC=C3)C4=CC=CC(=C4)C
- InChIKey:
- HEKAIDKUDLCBRU-UHFFFAOYSA-N
- PubChem:
- 9952773
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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