T-5224

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Selleck Chemicals

SKU:S8966-5MG

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T-5224 is an inhibitor of Interleukins and MMP used in studies of JAK-STAT Signaling and Immune Signaling. It is especially relevant in cancer, immunology, and inflammation models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses.

By inhibiting Interleukins and MMP, T-5224 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In cancer, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Interleukins and MMP
  • Pathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling
  • Concentration-response inhibition and target-dependence studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, T-5224 is appropriate when a defined chemical perturbant is needed to connect Interleukins and MMP with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Interleukins • MMP
Target Class:
Immunomodulator
Pathways:
JAK-STAT Signaling • Immune Signaling
Research Area:
Cancer • Immunology • Inflammation
CAS No.:
530141-72-1
Molecular Weight:
517.53
Formula:
C₂₉H₂₇NO₈
SMILES:
C1CCC(C1)OC2=CC(=C(C=C2)C(=O)C3=CC(=C(C=C3)OCC4=CC5=C(C=C4)C(=O)NO5)CCC(=O)O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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