Spermidine trihydrochloride

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Selleck Chemicals

SKU:S3653-25MG

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Spermidine trihydrochloride is an antagonist of NMDAR and Autophagy used in studies of Autophagy and Calcium Signaling. It is especially relevant in autophagy and neuroscience models, where defined compound exposure can be linked to autophagic flux, lysosomal turnover, and stress adaptation and calcium flux, excitability, and secretion-linked signaling.

By blocking NMDAR and Autophagy, Spermidine trihydrochloride can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In autophagy and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NMDAR and Autophagy
  • Pathway perturbation studies connected to Autophagy and Calcium Signaling
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Spermidine trihydrochloride is appropriate when a defined chemical perturbant is needed to connect NMDAR and Autophagy with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NMDAR • Autophagy
Target Class:
Ion Channel
Pathways:
Autophagy • Calcium Signaling
Research Area:
Autophagy • Neuroscience
CAS No.:
334-50-9
Molecular Weight:
254.63
Formula:
C₇H₁₉N₃·3HCl
SMILES:
C(CCNCCCN)CN.Cl.Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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