Sotagliflozin (LX4211)

1 1

Selleck Chemicals

S8103-5MG

€144,00 EUR
€144,00 EUR
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Sotagliflozin (LX4211) is an inhibitor of SGLT and SGLT1 and related targets used in studies of GPCR Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

By inhibiting SGLT and SGLT1 and related targets, Sotagliflozin (LX4211) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving SGLT and SGLT1 and related targets
  • Pathway perturbation studies connected to GPCR Signaling and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Sotagliflozin (LX4211) is appropriate when a defined chemical perturbant is needed to connect SGLT and SGLT1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
SGLT • SGLT1 • SGLT2
Target Class:
Transporter
Pathways:
GPCR Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
1018899-04-1
Molecular Weight:
424.94
Formula:
C₂₁H₂₅ClO₅S
SMILES:
CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)SC)O)O)O)Cl
InChIKey:
QKDRXGFQVGOQKS-UHFFFAOYSA-N
PubChem:
24831714
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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