SKLB-11A

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Selleck Chemicals

E5988-5MG

€193,00 EUR
€193,00 EUR
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SKLB-11A is an activator of Sirtuins used in studies of Epigenetic Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to chromatin-state control, histone modification, and transcriptional regulation in aging, cancer, and epigenetics models.

By activating Sirtuins, SKLB-11A can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In aging, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Sirtuins
  • Pathway perturbation studies connected to Epigenetic Regulation
  • Gain-of-function pathway-activation studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, SKLB-11A is appropriate when a defined chemical perturbant is needed to connect Sirtuins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Sirtuins
Target Class:
Epigenetic Regulator
Pathways:
Epigenetic Regulation
Research Area:
Aging • Cancer • Epigenetics • Metabolism
CAS No.:
433953-86-7
Molecular Weight:
350.35
Formula:
C₁₉H₁₅FN₄O₂
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.