SGI-7079

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Selleck Chemicals

S7847-5MG

€144,00 EUR
€144,00 EUR
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SGI-7079 is an inhibitor of RET and FLT3 used in studies of MAPK / ERK Signaling and JAK-STAT Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation in cancer and cell signaling models.

By inhibiting RET and FLT3, SGI-7079 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving RET and FLT3
  • Pathway perturbation studies connected to MAPK / ERK Signaling and JAK-STAT Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, SGI-7079 is appropriate when a defined chemical perturbant is needed to connect RET and FLT3 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
RET • FLT3
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling • JAK-STAT Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
1239875-86-5
Molecular Weight:
455.53
Formula:
C₂₆H₂₆FN₇
SMILES:
CC1=CNC2=NC(=NC(=C12)C3=CC=CC(=C3)CC#N)NC4=CC(=C(C=C4)N5CCN(CC5)C)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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