SC66

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Selleck Chemicals

SKU:S5313-10MG

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SC66 is an inhibitor of AKT used in studies of PI3K-Akt-mTOR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs in cancer, cell signaling, and metabolism models.

By inhibiting AKT, SC66 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving AKT
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, SC66 is appropriate when a defined chemical perturbant is needed to connect AKT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
AKT
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling
Research Area:
Cancer • Cell Signaling • Metabolism
CAS No.:
871361-88-5
Molecular Weight:
276.33
Formula:
C₁₈H₁₆N₂O
SMILES:
C1CC(=CC2=CC=NC=C2)C(=O)C(=CC3=CC=NC=C3)C1
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.