SB 265610

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Selleck Chemicals

S9516-5MG

€321,00 EUR
€321,00 EUR
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SB 265610 is an antagonist of CXCR and Interleukins used in studies of JAK-STAT Signaling and Immune Signaling and related signaling programs. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses.

By blocking CXCR and Interleukins, SB 265610 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and cytokine-mediated signaling and inflammatory effector responses. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CXCR and Interleukins
  • Pathway perturbation studies connected to JAK-STAT Signaling and Immune Signaling and related signaling programs
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, SB 265610 is appropriate when a defined chemical perturbant is needed to connect CXCR and Interleukins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CXCR • Interleukins
Target Class:
GPCR
Pathways:
JAK-STAT Signaling • Immune Signaling • GPCR Signaling
Research Area:
Immunology • Inflammation
CAS No.:
211096-49-0
Molecular Weight:
357.16
Formula:
C₁₄H₉BrN₆O
SMILES:
BrC1=CC=CC=C1NC(=O)NC2=CC=C(C#N)C3=C2[NH]N=N3
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.