Santacruzamate A (CAY10683)

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Selleck Chemicals

SKU:S7595-10MG

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Santacruzamate A (CAY10683) is an inhibitor of HDAC used in studies of DNA Damage Response and Epigenetic Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation in cancer, dna damage / repair, and epigenetics models.

By inhibiting HDAC, Santacruzamate A (CAY10683) can be used to examine checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HDAC
  • Pathway perturbation studies connected to DNA Damage Response and Epigenetic Regulation
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, Santacruzamate A (CAY10683) is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HDAC
Target Class:
Epigenetic Regulator
Pathways:
DNA Damage Response • Epigenetic Regulation
Research Area:
Cancer • DNA Damage / Repair • Epigenetics
CAS No.:
1477949-42-0
Molecular Weight:
278.35
Formula:
C₁₅H₂₂N₂O₃
SMILES:
CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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