Rhosin hydrochloride

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Selleck Chemicals

SKU:S8988-5MG

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Rhosin hydrochloride is an inhibitor of Rho GTPases used in studies of Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell cycle models.

By inhibiting Rho GTPases, Rhosin hydrochloride can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Rho GTPases
  • Pathway perturbation studies connected to Apoptosis
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in apoptosis, cancer, and cell cycle models

Overall, Rhosin hydrochloride is appropriate when a defined chemical perturbant is needed to connect Rho GTPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Rho GTPases
Target Class:
Other
Pathways:
Apoptosis
Research Area:
Apoptosis • Cancer • Cell Cycle • Cell Signaling
CAS No.:
1281870-42-5
Molecular Weight:
394.86
Formula:
C₂₀H₁₉ClN₆O
SMILES:
C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NN=CC3=CC4=NC=CN=C4C=C3)N.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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