Quetiapine (ICI-204636)fumarate

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Selleck Chemicals

S1763-25MG

€144,00 EUR
€144,00 EUR
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Quetiapine (ICI-204636)fumarate is an antagonist of Dopamine Receptors and Histamine Receptors and related targets used in studies of GPCR Signaling and Neurotransmission. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability in cardiovascular, inflammation, and neuroscience models.

By blocking Dopamine Receptors and Histamine Receptors and related targets, Quetiapine (ICI-204636)fumarate can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular, inflammation, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Dopamine Receptors and Histamine Receptors and related targets
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Quetiapine (ICI-204636)fumarate is appropriate when a defined chemical perturbant is needed to connect Dopamine Receptors and Histamine Receptors and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, inflammation, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Dopamine Receptors • Histamine Receptors • Adrenergic Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Cardiovascular • Inflammation • Neuroscience
CAS No.:
111974-72-2
Molecular Weight:
883.09
Formula:
C₄₆H₅₄N₆O₈S₂
SMILES:
C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3SC4=CC=CC=C42.C(=CC(=O)O)C(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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