PRT-060318 2HCl
Selleck Chemicals
SKU:S7738-5MG
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PRT-060318 2HCl is an inhibitor of SYK used in studies of Immune Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses in angiogenesis, cancer, and cell signaling models.
By inhibiting SYK, PRT-060318 2HCl can be used to examine cytokine-mediated signaling and inflammatory effector responses. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving SYK
- Pathway perturbation studies connected to Immune Signaling
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, PRT-060318 2HCl is appropriate when a defined chemical perturbant is needed to connect SYK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- SYK
- Target Class:
- Kinase
- Pathways:
- Immune Signaling
- Research Area:
- Angiogenesis • Cancer • Cell Signaling • Immunology
- CAS No.:
- 1194961-19-7 (free base)
- Molecular Weight:
- 413.34
- Formula:
- C₁₈H₂₄N₆O·2HCl
- SMILES:
- CC1=CC(=CC=C1)NC2=NC(=NC=C2C(=O)N)NC3CCCCC3N
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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