Pomalidomide (CC-4047)

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Selleck Chemicals

S1567-50MG

€186,00 EUR
€186,00 EUR
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Pomalidomide (CC-4047) is a modulator of E3 Ligase used in studies of NF-kB Signaling and Immune Signaling and related signaling programs. In practice, this places the compound in experiments that measure inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in apoptosis, cancer, and cell cycle models.

By modulating E3 Ligase, Pomalidomide (CC-4047) can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving E3 Ligase
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs
  • Context-dependent response profiling and mechanism comparison
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Pomalidomide (CC-4047) is appropriate when a defined chemical perturbant is needed to connect E3 Ligase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
E3 Ligase
Target Class:
Enzyme
Pathways:
NF-kB Signaling • Immune Signaling • Apoptosis
Research Area:
Apoptosis • Cancer • Cell Cycle • Immunology
CAS No.:
19171-19-8
Molecular Weight:
273.24
Formula:
C₁₃H₁₁N₃O₄
SMILES:
C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N
InChIKey:
UVSMNLNDYGZFPF-UHFFFAOYNA-N
PubChem:
134780
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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