Picrotoxin

1 1

Selleck Chemicals

S6100-25MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Shipping calculated at checkout.
Size
View full details

Picrotoxin is an antagonist of GABA Receptors used in studies of Neurotransmission. In practice, this places the compound in experiments that measure synaptic signaling, receptor activity, and neuronal excitability in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By blocking GABA Receptors, Picrotoxin can be used to examine synaptic signaling, receptor activity, and neuronal excitability. This context is compatible with electrophysiology, neurotransmission, and receptor-response assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving GABA Receptors
  • Pathway perturbation studies connected to Neurotransmission
  • Receptor-blockade and ligand-competition studies
  • Phenotypic profiling in neuroscience models

Overall, Picrotoxin is appropriate when a defined chemical perturbant is needed to connect GABA Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
GABA Receptors
Target Class:
Other
Pathways:
Neurotransmission
Research Area:
Neuroscience
CAS No.:
124-87-8
Molecular Weight:
602.58
Formula:
C₁₅H₁₈O₇·C₁₅H₁₆O₆
SMILES:
C=C(C)[C@@H]1C2OC(=O)C1[C@]1(O)CC3O[C@]34C(=O)O[C@H]2[C@]14C.CC(C)(O)[C@@H]1C2OC(=O)C1[C@]1(O)C[C@H]3O[C@]34C(=O)O[C@H]2[C@]14C
InChIKey:
VJKUPQSHOVKBCO-ZTYBEOBUSA-N
PubChem:
31304
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.