PF 4800567

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Selleck Chemicals

S2249-5MG

€144,00 EUR
€144,00 EUR
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PF 4800567 is an inhibitor of CK2 used in studies of Wnt Signaling. It is especially relevant in cancer, cell signaling, and developmental biology models, where defined compound exposure can be linked to beta-catenin-dependent transcription and developmental signaling.

By inhibiting CK2, PF 4800567 can be used to examine beta-catenin-dependent transcription and developmental signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CK2
  • Pathway perturbation studies connected to Wnt Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, PF 4800567 is appropriate when a defined chemical perturbant is needed to connect CK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CK2
Target Class:
Kinase
Pathways:
Wnt Signaling
Research Area:
Cancer • Cell Signaling • Developmental Biology • Stem Cell Biology
CAS No.:
1188296-52-7
Molecular Weight:
359.81
Formula:
C₁₇H₁₈ClN₅O₂
SMILES:
C1COCCC1N2C3=NC=NC(=C3C(=N2)COC4=CC(=CC=C4)Cl)N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.