P2RX1 (P2X1) Antibody - Western Blot Validated
BiCell Scientific
SKU:15161-WB-50UL
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Scientific Overview
For consistent comparison across experiments, use this antibody to explore P2RX1 (P2X1) with a repeatable workflow. P2RX1 is a channel or transporter associated with regulated flux across cellular membranes. Use matched handling so differences reflect biology rather than processing.
Following P2RX1 across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
When building a narrative around the target, it helps to track:
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
- relative abundance across engineered constructs
Application-Specific Context
This denaturing-format version is geared toward targets presented after reduction and denaturation, where epitope exposure can shift from native conformations. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.
If your study spans multiple model systems, it can help to define a shared reference condition for P2RX1 so cross-sample contrasts stay meaningful.
Pair this denaturing-format format with stable controls to keep P2RX1 (P2X1) measurements coherent over time.
- Targets:
- P2RX1
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (12-aa) derived from the C-terminal cytoplasmic region of human P2RX1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P51575
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C