Oncrasin-1

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Selleck Chemicals

SKU:S0780-5MG

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Oncrasin-1 is an inhibitor of DNA/RNA Synthesis and KRAS used in studies of MAPK / ERK Signaling and DNA Damage Response. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control in cancer, cell cycle, and cell signaling models.

By inhibiting DNA/RNA Synthesis and KRAS, Oncrasin-1 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving DNA/RNA Synthesis and KRAS
  • Pathway perturbation studies connected to MAPK / ERK Signaling and DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Oncrasin-1 is appropriate when a defined chemical perturbant is needed to connect DNA/RNA Synthesis and KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
DNA/RNA Synthesis • KRAS
Target Class:
Enzyme
Pathways:
MAPK / ERK Signaling • DNA Damage Response
Research Area:
Cancer • Cell Cycle • Cell Signaling • DNA Damage / Repair
CAS No.:
75629-57-1
Molecular Weight:
269.73
Formula:
C₁₆H₁₂ClNO
SMILES:
C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C=O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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