ODM-203

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Selleck Chemicals

SKU:S8882-5MG

Regular price €154,00 EUR
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ODM-203 is an inhibitor of FGFR and FGFR1 and related targets used in studies of MAPK / ERK Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in angiogenesis, cancer, and cell signaling models.

By inhibiting FGFR and FGFR1 and related targets, ODM-203 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving FGFR and FGFR1 and related targets
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, ODM-203 is appropriate when a defined chemical perturbant is needed to connect FGFR and FGFR1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
FGFR • FGFR1 • FGFR2 • FGFR3
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling
Research Area:
Angiogenesis • Cancer • Cell Signaling
CAS No.:
1430723-35-5
Molecular Weight:
505.54
Formula:
C₂₆H₂₁F₂N₅O₂S
SMILES:
CN1C=C(C=N1)C2=CC3=C(C=C2)N(C=N3)C4=CC(=CC(=C4)NS(=O)(=O)C5CC5)C6=C(C=C(C=C6)F)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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