Norfloxacin

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Selleck Chemicals

SKU:S1509-50MG

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Norfloxacin is a modulator of Topoisomerase used in studies of DNA Damage Response. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer, dna damage / repair, and infectious disease models.

By modulating Topoisomerase, Norfloxacin can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Topoisomerase
  • Pathway perturbation studies connected to DNA Damage Response
  • Context-dependent response profiling and mechanism comparison
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Norfloxacin is appropriate when a defined chemical perturbant is needed to connect Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Topoisomerase
Target Class:
Enzyme
Pathways:
DNA Damage Response
Research Area:
Cancer • DNA Damage / Repair • Infectious Disease
CAS No.:
70458-96-7
Molecular Weight:
319.33
Formula:
C₁₆H₁₈FN₃O₃
SMILES:
CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O
InChIKey:
OGJPXUAPXNRGGI-UHFFFAOYSA-N
PubChem:
4539
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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