Nodakenetin

1 1

Selleck Chemicals

S3245-1MG

€173,00 EUR
€173,00 EUR
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Nodakenetin is an inhibitor of BCL-2 used in studies of Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and metabolism models.

By inhibiting BCL-2, Nodakenetin can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BCL-2
  • Pathway perturbation studies connected to Apoptosis
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in apoptosis, cancer, and metabolism models

Overall, Nodakenetin is appropriate when a defined chemical perturbant is needed to connect BCL-2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BCL-2
Target Class:
Other
Pathways:
Apoptosis
Research Area:
Apoptosis • Cancer • Metabolism
CAS No.:
495-32-9
Molecular Weight:
246.26
Formula:
C₁₄H₁₄O₄
SMILES:
CC(C)(O)C1CC2=C(O1)C=C3OC(=O)C=CC3=C2
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.