Nilutamide

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Selleck Chemicals

S4836-25MG

€95,00 EUR
€95,00 EUR
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Nilutamide is an antagonist of Androgen Receptor used in studies of Hormone Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ligand-dependent transcriptional programs and endocrine regulation in cancer and endocrinology models.

By blocking Androgen Receptor, Nilutamide can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cancer and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Androgen Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Receptor-blockade and ligand-competition studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Nilutamide is appropriate when a defined chemical perturbant is needed to connect Androgen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Androgen Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Cancer • Endocrinology
CAS No.:
63612-50-0
Molecular Weight:
317.22
Formula:
C₁₂H₁₀F₃N₃O₄
SMILES:
CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C
InChIKey:
XWXYUMMDTVBTOU-UHFFFAOYSA-N
PubChem:
4493
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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