MT-802

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Selleck Chemicals

SKU:S6966-5MG

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MT-802 is an inhibitor of BTK used in studies of Immune Signaling and Protein Degradation / Proteasome. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-mediated signaling and inflammatory effector responses and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation in angiogenesis, cancer, and cell signaling models.

By inhibiting BTK, MT-802 can be used to examine cytokine-mediated signaling and inflammatory effector responses and ubiquitin-dependent turnover, proteostasis, and targeted protein degradation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BTK
  • Pathway perturbation studies connected to Immune Signaling and Protein Degradation / Proteasome
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, MT-802 is appropriate when a defined chemical perturbant is needed to connect BTK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BTK
Target Class:
Kinase
Pathways:
Immune Signaling • Protein Degradation / Proteasome
Research Area:
Angiogenesis • Cancer • Cell Signaling • Immunology
CAS No.:
2231744-29-7
Molecular Weight:
787.82
Formula:
C₄₁H₄₁N₉O₈
SMILES:
NC1=C2C(=NC=N1)[N](N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CCN(CCOCCOCC(=O)NC6=CC7=C(C=C6)C(=O)N(C8CCC(=O)NC8=O)C7=O)CC5
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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