MRT67307

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Selleck Chemicals

S6386-5MG

€144,00 EUR
€144,00 EUR
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MRT67307 is an inhibitor of IKK used in studies of NF-kB Signaling and Immune Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses in autophagy, immunology, and inflammation models.

By inhibiting IKK, MRT67307 can be used to examine inflammatory transcriptional control and stress-responsive survival signaling and cytokine-mediated signaling and inflammatory effector responses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In autophagy, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving IKK
  • Pathway perturbation studies connected to NF-kB Signaling and Immune Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, MRT67307 is appropriate when a defined chemical perturbant is needed to connect IKK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
IKK
Target Class:
Signaling Pathway Modulator
Pathways:
NF-kB Signaling • Immune Signaling • Autophagy
Research Area:
Autophagy • Immunology • Inflammation
CAS No.:
1190378-57-4
Molecular Weight:
464.60
Formula:
C₂₆H₃₆N₆O₂
SMILES:
O=C(NCCCNC1=NC(=NC=C1C2CC2)NC3=CC=CC(=C3)CN4CCOCC4)C5CCC5
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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