Monastrol

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Selleck Chemicals

S8439-10MG

€144,00 EUR
€144,00 EUR
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Monastrol is an inhibitor of Kinesins used in studies of Cell Cycle Regulation. It is especially relevant in cancer and cell cycle models, where defined compound exposure can be linked to checkpoint control, mitotic progression, and proliferation timing.

By inhibiting Kinesins, Monastrol can be used to examine checkpoint control, mitotic progression, and proliferation timing. This context is compatible with cell-cycle, mitotic, and proliferation assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Kinesins
  • Pathway perturbation studies connected to Cell Cycle Regulation
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer and cell cycle models

Overall, Monastrol is appropriate when a defined chemical perturbant is needed to connect Kinesins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Kinesins
Target Class:
Other
Pathways:
Cell Cycle Regulation
Research Area:
Cancer • Cell Cycle
CAS No.:
329689-23-8
Molecular Weight:
292.35
Formula:
C₁₄H₁₆N₂O₃S
SMILES:
CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C
InChIKey:
LOBCDGHHHHGHFA-LBPRGKRZSA-N
PubChem:
794323
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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