ML367

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Selleck Chemicals

S0161-5MG

€449,00 EUR
€449,00 EUR
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ML367 is an inhibitor of ATPases used in studies of DNA Damage Response. In practice, this places the compound in experiments that measure checkpoint activation, DNA repair, and genome-stability control in cancer, cell signaling, and dna damage / repair models.

By inhibiting ATPases, ML367 can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ATPases
  • Pathway perturbation studies connected to DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, ML367 is appropriate when a defined chemical perturbant is needed to connect ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ATPases
Target Class:
Enzyme
Pathways:
DNA Damage Response
Research Area:
Cancer • Cell Signaling • DNA Damage / Repair
CAS No.:
381168-77-0
Molecular Weight:
334.32
Formula:
C₁₉H₁₂F₂N₄
SMILES:
C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=NC=C3)NC4=CC(=C(C=C4)F)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.