MC180295

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Selleck Chemicals

SKU:S8809-2MG

Regular price €144,00 EUR
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MC180295 is an inhibitor of CDK9 and CDK and related targets used in studies of Cell Cycle Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint control, mitotic progression, and proliferation timing in cancer, cell cycle, and cell signaling models.

By inhibiting CDK9 and CDK and related targets, MC180295 can be used to examine checkpoint control, mitotic progression, and proliferation timing. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving CDK9 and CDK and related targets
  • Pathway perturbation studies connected to Cell Cycle Regulation
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, MC180295 is appropriate when a defined chemical perturbant is needed to connect CDK9 and CDK and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
CDK9 • CDK • CDK1 • CDK2
Target Class:
Kinase
Pathways:
Cell Cycle Regulation
Research Area:
Cancer • Cell Cycle • Cell Signaling
CAS No.:
2237942-08-2
Molecular Weight:
358.41
Formula:
C₁₇H₁₈N₄O₃S
SMILES:
C1CC2CC1CC2NC3=NC(=C(S3)C(=O)C4=CC=CC=C4[N+](=O)[O-])N
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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