Manidipine

1 1

Selleck Chemicals

S2481-10MG

€144,00 EUR
€144,00 EUR
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Manidipine is an inhibitor of Calcium Channels used in studies of Calcium Signaling. It is especially relevant in cardiovascular, cell signaling, and neuroscience models, where defined compound exposure can be linked to calcium flux, excitability, and secretion-linked signaling.

By inhibiting Calcium Channels, Manidipine can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cardiovascular, cell signaling, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Calcium Channels
  • Pathway perturbation studies connected to Calcium Signaling
  • Concentration-response inhibition and target-dependence studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, Manidipine is appropriate when a defined chemical perturbant is needed to connect Calcium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, cell signaling, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Calcium Channels
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Cardiovascular • Cell Signaling • Neuroscience
CAS No.:
89226-50-6
Molecular Weight:
610.7
Formula:
C₃₅H₃₈N₄O₆
SMILES:
CC1=C(C(C(=C(N1)C)C(=O)OCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4)C5=CC(=CC=C5)[N+](=O)[O-])C(=O)OC
InChIKey:
ANEBWFXPVPTEET-UHFFFAOYSA-N
PubChem:
4008
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.