Losartan Carboxylic Acid (EXP-3174)

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Selleck Chemicals

S5980-5MG

€97,00 EUR
€97,00 EUR
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Losartan Carboxylic Acid (EXP-3174) is an antagonist of Angiotensin Receptors used in studies of GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular models.

By blocking Angiotensin Receptors, Losartan Carboxylic Acid (EXP-3174) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Angiotensin Receptors
  • Pathway perturbation studies connected to GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Losartan Carboxylic Acid (EXP-3174) is appropriate when a defined chemical perturbant is needed to connect Angiotensin Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Angiotensin Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling
Research Area:
Cardiovascular
CAS No.:
124750-92-1
Molecular Weight:
436.89
Formula:
C₂₂H₂₁ClN₆O₂
SMILES:
CCCCC1=NC(=C([N]1CC2=CC=C(C=C2)C3=CC=CC=C3C4=N[NH]N=N4)C(O)=O)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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