Lomibuvir (VX-222)

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Selleck Chemicals

S1480-5MG

€167,00 EUR
€167,00 EUR
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Lomibuvir (VX-222) is an inhibitor of HCV Protease used in studies of Viral Entry / Replication. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to host-pathogen interactions, entry mechanisms, and replication-associated responses in infectious disease models.

By inhibiting HCV Protease, Lomibuvir (VX-222) can be used to examine host-pathogen interactions, entry mechanisms, and replication-associated responses. The protease annotation adds relevance to protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping in the same experimental setting. In infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HCV Protease
  • Pathway perturbation studies connected to Viral Entry / Replication
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays

Overall, Lomibuvir (VX-222) is appropriate when a defined chemical perturbant is needed to connect HCV Protease with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HCV Protease
Target Class:
Protease
Pathways:
Viral Entry / Replication
Research Area:
Infectious Disease
CAS No.:
1026785-59-0
Molecular Weight:
445.61
Formula:
C₂₅H₃₅NO₄S
SMILES:
CC1CCC(CC1)C(=O)N(C2CCC(CC2)O)C3=C(SC(=C3)C#CC(C)(C)C)C(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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