Loganin

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Selleck Chemicals

SKU:S3835-10MG

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Loganin is an inhibitor of BACE used in studies of protease biology. It is especially relevant in neuroscience models, where defined compound exposure can be linked to proteolytic processing and cleavage-dependent signaling. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation. This is particularly useful during early mechanism mapping and focused panel construction.

By inhibiting BACE, Loganin can be used to examine proteolytic processing and cleavage-dependent signaling. This target class is commonly examined through protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving BACE
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays
  • Phenotypic profiling in neuroscience models

Overall, Loganin is appropriate when a defined chemical perturbant is needed to connect BACE with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
BACE
Target Class:
Protease
Research Area:
Neuroscience
CAS No.:
18524-94-2
Molecular Weight:
390.38
Formula:
C₁₇H₂₆O₁₀
SMILES:
CC1C(CC2C1C(OC=C2C(=O)OC)OC3C(C(C(C(O3)CO)O)O)O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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