Leupeptin Hemisulfate

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Selleck Chemicals

S7380-10MG

€144,00 EUR
€144,00 EUR
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Leupeptin Hemisulfate is an inhibitor of Serine Proteases and Cysteine Proteases used in studies of protease biology. It is especially relevant in inflammation models, where defined compound exposure can be linked to proteolytic processing and cleavage-dependent signaling.

By inhibiting Serine Proteases and Cysteine Proteases, Leupeptin Hemisulfate can be used to examine proteolytic processing and cleavage-dependent signaling. This target class is commonly examined through protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping. In inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Serine Proteases and Cysteine Proteases
  • Concentration-response inhibition and target-dependence studies
  • Protease-activity, cleavage, and substrate-processing assays
  • Phenotypic profiling in inflammation models

Overall, Leupeptin Hemisulfate is appropriate when a defined chemical perturbant is needed to connect Serine Proteases and Cysteine Proteases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Serine Proteases • Cysteine Proteases
Target Class:
Protease
Research Area:
Inflammation
CAS No.:
103476-89-7
Molecular Weight:
475.59
Formula:
C₂₀H₃₈N₆O₄·½H₂SO₄
SMILES:
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C.CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C=O)NC(=O)C.OS(=O)(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.