L-778123 hydrochloride

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Selleck Chemicals

SKU:E4620-5MG

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L-778123 hydrochloride is an inhibitor of Transferases used in studies of DNA Damage Response and Metabolic Signaling. It is especially relevant in cancer, dna damage / repair, and metabolism models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and metabolic regulation, energy sensing, and enzyme-linked homeostasis.

By inhibiting Transferases, L-778123 hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Transferases
  • Pathway perturbation studies connected to DNA Damage Response and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, L-778123 hydrochloride is appropriate when a defined chemical perturbant is needed to connect Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Transferases
Target Class:
Enzyme
Pathways:
DNA Damage Response • Metabolic Signaling
Research Area:
Cancer • DNA Damage / Repair • Metabolism
CAS No.:
253863-00-2
Molecular Weight:
442.34
Formula:
C₂₂H₂₀ClN₅O·ClH
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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