KT-474 (SAR444656)

1 1

Selleck Chemicals

E1655-1MG

€193,00 EUR
€193,00 EUR
Sale Sold out
Shipping calculated at checkout.
Size
View full details

KT-474 (SAR444656) is a modulator of TLR and Interleukins used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. It is especially relevant in immunology and inflammation models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling.

By modulating TLR and Interleukins, KT-474 (SAR444656) can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TLR and Interleukins
  • Pathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs
  • Context-dependent response profiling and mechanism comparison
  • Immune-cell activation, cytokine, and mediator assays

Overall, KT-474 (SAR444656) is appropriate when a defined chemical perturbant is needed to connect TLR and Interleukins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TLR • Interleukins
Target Class:
Immunomodulator
Pathways:
JAK-STAT Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Immunology • Inflammation
CAS No.:
2432994-31-3
Molecular Weight:
865.93
Formula:
C₄₄H₄₉F₂N₁₁O₆
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.