KCNB1 (Kv2.1) Antibody

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BiCell Scientific

SKU:20231-50UL

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Size
Blocking Peptide
Quantity
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Scientific Overview

Build reproducible readouts by using this antibody to characterize KCNB1 across matched sample sets. KCNB1 is a channel or transporter associated with regulated flux across cellular membranes. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.

Tracking KCNB1 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.

Research Relevance

Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.

Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes.

When building a narrative around the target, it helps to track:

  • relative abundance across engineered constructs
  • patterns consistent with apical or basolateral sorting
  • stimulus-dependent trafficking and turnover
  • surface versus intracellular pool distribution

Application-Specific Context

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. A short pilot series can help set exposure ranges and reduce reruns.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so KCNB1 patterns can be compared across experiments without guesswork.

For multi-run studies, the regular format option helps keep KCNB1 trends comparable from experiment to experiment.

Targets:
KCNB1
Research Area:
Neuroscience
Application:
IF • IHC • WB
Reactivity:
Human • Mouse • Rat
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (14-aa) derived from the C-terminal region of human Kv2.1 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q14721
Homology:
Synthetic peptide sequence is identical to mouse or rat sequence
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C