KCNA7 (Kv1.7) Antibody
BiCell Scientific
SKU:20227-50UL
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Biological Background
When you need to characterize KCNA7 with attention to cellular organization, this antibody provides a focused option. KCNA7 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking KCNA7 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Use in the Laboratory
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Many targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.
To keep datasets interpretable, labs often document:
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
- stimulus-dependent trafficking and turnover
Version Notes
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.
When interpreting KCNA7, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the regular format variant when your project demands KCNA7 readouts that respect preparation constraints.
- Targets:
- KCNA7
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of mouse Kv1.7 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q96RP8
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 85.7% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C