KCNA1 (Kv1.1) Antibody - Western Blot Validated
BiCell Scientific
SKU:20221-WB-50UL
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Protein Function
When you need to assess KCNA1 with attention to cellular organization, this antibody provides a focused option. KCNA1 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Following KCNA1 across perturbations can help separate expression effects from compartment shifts.
Experimental Applications
Transport targets are commonly studied under stimulation conditions that alter membrane potential, osmolarity, or nutrient availability. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Common experimental questions that benefit from target tracking include:
- relative abundance across engineered constructs
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
Workflow Perspective
If your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series.
When interpreting KCNA1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
As you refine hypotheses around KCNA1, the denaturing-format format helps keep conclusions tied to preparation context.
- Targets:
- KCNA1
- Research Area:
- Neuroscience
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of mouse Kv1.1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q09470
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 92.9% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C